产品货号：
Z17546
中文名称：
GSTA1/A2/A3/A4/A5抗体
英文名称：
Anti-GSTA1/A2/A3/A4/A5 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GSTA1/A2/A3/A4/A5 Antibody |
| 指标别名 | Glutathione S-transferase A1;2.5.1.18;GST HA subunit 1;GST class-alpha member 1;GST-epsilon;GSTA1-1;GTH1;Glutathione S-transferase A1;N-terminally processed;GSTA1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ELISA(Cap) |
| 基因名称 | GSTA1/GSTA2/GSTA3/GSTA4/GSTA5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human GSTA1/A2/A3/A4/A5 recombinant protein (Position:A2-F222). |
| 实际分子量 | 25KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families.These enzymes function in the detoxification of electrophilic compounds,including carcinogens,therapeutic drugs,environmental toxins and products of oxidative stress,by conjugation with glutathione.The genes encoding these enzymes are known to be highly polymorphic.These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs.At present,eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified:alpha,kappa,mu,omega,pi,sigma,theta and zeta.This gene encodes a glutathione S-tranferase belonging to the alpha class.The alpha class genes,located in a cluster mapped to chromosome 6,are the most abundantly expressed glutathione S-transferases in liver.In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver,the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. |
| Uniprot ID | P08263/P09210/Q16772/O15217/Q7RTV2 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 ELISA(Cap) 1:50～1:200 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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